李玉安，扬州大学“青年百人”特聘教授，博士生导师。

主要研究方向：1. 工程菌多场景递送平台开发；2. 细菌-宿主先天免疫系统互作/逃逸机制。

主持国家自然科学基金青年基金、江苏省自然科学基金青年基金、动物基因工程疫苗国家重点实验室开放课题、扬州大学高层次人才科研启动基金项目；参与国家重点研发计划重点专项课题，国家自然科学基金面上项目等国家级科研项目多项。

以第一作者身份在 Advanced Science (2025, 2023)、Veterinary Research (2022, 2017)、Veterinary Microbiology (2025, 2023)和Vaccine等期刊上发表 SCI 论文8篇，指导学生或合作发表SCI论文共17篇；授权国家发明专利2项。

代表性论文：

1. Li Yu-An, Yi F, Wenjing L,Zhang Y, Wang S, Curtiss R, Shi H. A purely biomanufactured system for delivering nanoparticles and STING agonists. Adv Sci (Weinh). 2025 Jan;12(3):e2408539. 一区，IF: 15.6

2. Li Yu-An, Sun Y, Zhang Y, Li Q, Wang S, Curtiss R, Shi H. A Bacterial mRNA-Lysis-Mediated Cargo Release Vaccine System for Regulated Cytosolic Surveillance and Optimized Antigen Delivery. Adv Sci (Weinh). 2023 Nov;10(33):e2303568. 一区，IF: 15.6

3. Li Yu-An, Sun Y, Fu Y, Zhang Y, Li Q, Wang S, Shi H. Salmonella enterica serovar Choleraesuis vector delivering a dual-antigen expression cassette provides mouse cross-protection against Streptococcus suis serotypes 2, 7, 9, and 1/2. Vet Res. 2022 Jun 22;53(1):46. 一区，IF: 4.0

4. Li Yu-An, Ji Z, Wang X, Wang S, Shi H. Salmonella enterica serovar Choleraesuis vector delivering SaoA antigen confers protection against Streptococcus suis serotypes 2 and 7 in mice and pigs. Vet Res. 2017 Dec 21;48(1):89. 一区，IF: 4.0

5. Li Yu-An, Feng Y, Ouyang H, Zhang Y, Shi H. Signal peptides enhance immunogenicity and protection of recombinant Salmonella enterica serovar Choleraesuis vectors against Streptococcus suis. Vet Microbiol. 2025 Jul 19;308:110650. 二区，IF: 2.9

6. Li Yu-An, Sun Y, Zhang Y, Wang X, Dieye Y, Wang S, Shi H. Salmonella enterica serovar Choleraesuis vector outperforms alum as an adjuvant, increasing a cross-protective immune response against Glaesserella parasuis. Vet Microbiol. 2023 Nov 22;287:109915. pii: S0378-1135(23)00269-9. doi: 10.1016/j.vetmic.2023.109915. 二区，IF: 2.9

7. Li Yu-An, Sun Y, Zhang Y, Li Q, Wang S, Shi H. Live attenuated Salmonella enterica serovar Choleraesuis vector delivering a virus-like particles induces a protective immune response against porcine circovirus type 2 in mice. Vaccine, 2022, ISSN 0264-410X.  三区，IF: 3.5

8. Li Yu-An, Chen Y, Du YZ, Guo W, Chu D, Fan J, Wang X, Bellefleur M, Wang S, Shi H. Live-attenuated Salmonella enterica serotype Choleraesuis vaccine with regulated delayed fur mutation confer protection against Streptococcus suis in mice. BMC Vet Res. 2020 May 7;16(1):129. 二区，IF: 2.7

9. Li W, Li Yu-An, Zhang Y, Shi H. Engineered Salmonella Enteritidis vector targeting innate immune molecules provides protection against Salmonella Enteritidis and Salmonella Typhimurium. Poult Sci. 2025 Aug 24;104(11):105724. 一区，IF: 4.5

10. Sun W, Li Yu-An, Li Z, Li G, Du Y, Shi H. Recombinant Salmonella vector delivery 3M2e-ferritin fusion nanoparticles provide cross protection against H9N2 and H7N9 avian influenza viruses. Vet Microbiol. 2025 May 5;305:110546. 二区，IF: 2.9

11. Li W, Li Yu-An, Wang S, Shi H. A universal live vaccine platform against multiple serotypes Streptococcus suis based on polyvalent antigen protein. Vaccine. 2025 Jan 7;47:126700. 三区，IF: 3.5