李金贵，2001年毕业于中国农业大学动物医学院，获农学博士学位，同年入职扬州大学，2004年被评为副教授，2010年晋升为教授；现扬州大学兽医学院博士研究生导师。昆士兰大学生物医学院访问学者，农业农村部第七届新兽药评审委员会委员，第八届全国兽医专业学位优秀硕士论文指导教师，国家自然基金面上项目通讯评审专家，江苏省青蓝工程骨干教师，江苏省高校优秀本科毕业论文一等奖指导教师。江苏省高校动物重要疫病与人畜共患病防控协同创新中心以及教育部农业与农产品安全国际联合实验室PI，中国畜牧兽医学会中兽医分会常务理事。

为本科生和研究生主讲《中兽医学》、《新兽药创制》、《中兽医学进展》、《中药药理学》等课程，主要开展中（兽）药替抗、免疫增效、创新药物靶向递送以及针灸效应机制等研究工作，主持完成多项国家自然科学基金项目和横向科研课题。

近年来主持和参加的主要科研项目情况：

(1) 国家自然科学基金面上项目，基于巨噬细胞M2极化调控研究青蒿琥酯促进肠黏膜损伤修复的作用机制，2021-01至2024-12，在研，主持

(2) 国家重点研发计划专项，中兽医药现代化与绿色养殖技术研究（子项目），2017-07至2020-12，已结题，参加

(3) 国家重点研发计划专项，畜禽药物代谢转归和耐药性形成机制（子项目），2018-01至2020.12，已结题，主持

(4) 国家自然科学基金面上项目基于ERS-UPR信号通路研究青蒿素类药物调控溃疡性结肠炎的分子机制，2016-01至2020-12，已结题，主持

(5) 国家自然科学基金面上项目，调控鸡球虫性别分化与发育相关蛋白基因的克隆与鉴定. 2015-01至2018-12，已结题，参加

(6) 横向合作项目，辣木提取物抗溃疡性结肠炎作用机制研究，2022-07至2025-12，在研，主持

(7) 横向合作项目，抗球虫天然植物提取物及其作用机制研究，2023-03至2025-07，在研，主持

近年来以通顺作者发表的主要论文：

Ya Tao, Lei Xu, Xiaopan Liu, Peijia Wang, Simin Wei, Yinmo Huang, Wenyi Gu, Ruonan Bo, Mingjiang Liu, Jie Yu*, Jingui Li*. Chitosan-coated artesunate protects against ulcerative colitis via STAT6-mediated macrophage M2 polarization and intestinal barrier protection. International Journal of Biological Macromolecules. 2024, 254, 127680.

Huang JJ, Feng YM, Zheng SM, Yu CL, Zhou RG, Liu MJ, Bo RN, Yu J, Li JG. Eugenol possesses colitis protective effects: impacts on the TLR4/MyD88/NF-κB pathway, intestinal epithelial barrier, and macrophage polarization. Am J Chin Med. 2024 Mar 14:1-20. doi: 10.1142/S0192415X24500216. 

Ruonan Bo, Jing Wang, Luming Rui, Xiaopan Liu, Jiawen Li, Ya Tao, Hailong Hong, Shuya Xu, Meng Huang, Mingjiang Liu, Huan Pang*, Jingui Li*. Journal of Drug Delivery Science and Technology. 2023, 82, 104192.

RuoNan Bo#, YiWen Zhan#, SiMin Wei, ShuYa Xu, YinMo Huang, MingJiang Liu and JinGui Li. Tea tree oil nanoliposomes: optimization, characterization, and antibacterial activity against Escherichia coli in vitro and in vivo. Poultry Science. 2023, 102:102238.

Ya Tao, Xin Zhao, XiaoPan Liu, PeiJia Wang, YinMo Huang, RuoNan Bo, MingJiang Liu, JinGui Li. Oral delivery of chitosan-coated PLGA nanoemulsion loaded with artesunate alleviates ulcerative colitis in mice. Colloids and Surfaces B: Biointerfaces. 2022, 219, 112824

Wei Simin, Tian Qiming, Zhao Xin, Liu Xiaopan, Husien HM, Liu Mingjiang, Bo Ruonan, Li Jingui*.  Tea Tree Oil Nanoemulsion Potentiates Antibiotics against Multidrug-Resistant Escherichia coli. ACS Infect Dis. 2022 Aug 12;8(8):1618-1626.

Huang Junjie, Huang Jie, Husien HM, Peng Weilong, Liu Mingjiang, Bo Ruonan, Li Jingui*.  Comparison of endogenous development, invasion ability and apoptotic features between diclazuril resistant and sensitive strains of Eimeria tenella. Vet Parasitol. 2022, 305: 109719.

Xin Zhao, ShuMei Zheng, SiMin Wei, QiMing Tian, Ya Tao, RuoNan Bo, MingJiang Liu, JinGui Li*. The protective effects and potential mechanisms of eugenol against Salmonella in vivo and in vitro. Poultry Science. 2022, 101: 101801.

Xin Zhao, SiMin Wei, QiMing Tian, WeiLong Peng, Ya Tao, RuoNan Bo, JinGui Li*. Eugenol exposure in vitro inhibits the expressions of T3SS and TIF virulence genes in Salmonella Typhimurium and reduces its pathogenicity to chickens. Microb Pathog. 2022, 162: 105314.

Ruonan Bo, Xun Ji, Haifeng Yang, Mingjiang Liu, Jingui Li*. The characterization of optimal selenized garlic polysaccharides and its immune and antioxidant activity in chickens. International Journal of Biological Macromolecules. 2021, 182: 136–143.

Shaojie Yin, Liuhui Li, Ya Tao, Jie Yu, Simin Wei, Mingjiang Liu and Jingui Li*. The Inhibitory Effect of Artesunate on Excessive Endoplasmic Reticulum Stress Alleviates Experimental Colitis in Mice. Frontiers in Pharmacology. 2021, 12: 629798.

Mingjiang Liu, Chi Zhang, Xiaolong Xu, Xin Zhao, Ziyi Han, Dandan Liu, Ruonan Bo, Jingui Li*, Zongping Liu*. Ferulic acid inhibits LPS‑induced apoptosis in bovine mammary epithelial cells by regulating the NF‑κB and Nrf2 signalling pathways to restore mitochondrial dynamics and ROS generation. Veterinary Research. 2021, 52:104.

SiMin Wei, Xin Zhao, Jie Yu, ShaoJie Yin, MingJiang Liu, RuoNan Bo, JinGui Li*. Characterization of tea tree oil nanoemulsion and its acute and subchronic toxicity. Regulatory Toxicology and Pharmacology. 2021,124: 104999.

Yin Shaojie, Yang Haifeng, Tao Ya, Wei Simin, Li Liuhui, Liu Mingjiang, Li Jingui*. Artesunate ameliorates DSS-induced ulcerative colitis by protecting intestinal barrier and inhibiting inflammatory response. Inflammation. 2020, 43(2):765-776.

合作发表主要论文：

1. Xiaoyu Lu, Yufeng Du, Kai Peng, Wenhui Zhang, Jingui Li, Zhiqiang Wang, Ruichao Li*. Coexistence of tet(X4), mcr-1, and blaNDM-5 in ST6775 Escherichia coli Isolates of Animal Origin in China. Microbiol Spectr. 2022 Apr 27;10(2):e0019622.

2. Liu M, Liu T, Wang X, Yu C, Qin T, Li J, Zhang M, Li Z, Cui X, Xu X* and Liu Q*.  Cangma Huadu granules attenuate H1N1 virus-induced severe lung injury correlated with repressed apoptosis and altered gut microbiome. Front. Microbiol. 13:947112.