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个人信息Personal Information
副高级
硕士生导师
教师拼音名称:Li Chenxi
电子邮箱:
所在单位:兽医学院
学历:博士研究生毕业
办公地点:扬州大学荷花池校区逸夫图书馆二楼205
性别:男
学位:农学博士学位
在职信息:在岗
毕业院校:中国农业科学院
其他联系方式Other Contact Information
通讯/办公地址 :
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个人简介Personal Profile
个人简介:
李晨曦,中共党员,博士,副教授,硕士生导师; 2010-2014年就读于吉林大学获理学学士学位;2014-2020年就读于中国农业科学院获农学博士学位。目前主要从事兽医微生物学与免疫学相关的教 学和科研工作,研究方向聚焦于蚊媒病毒-黄病毒(日本脑炎病毒JEV与坦布苏病毒TMUV)的致病机制、免疫应答机制及抗病毒药物筛选等方面的工作。主持包括国家自然科学基金,“十四五国家重点研 发计划”子课题等在内的项目共6项。获扬州大学高层次人才科研启动项目与扬州市“绿杨金凤”优秀博士项目资助。以第一作者或通讯作者在《Advanced Science》,《PLoS Pathogens》,《mBio》等杂志发表SCI论文16篇,累计发表SCI论文40余篇(论文列表:https://www.ncbi.nlm.nih.gov/myncbi/collections/mybibliography/)。申请发明专利8项,授权发明专利5项。担任《Zoonoses》、《Animals and Zoonoses》期刊青年编委;担任《Emerging Microbes & Infections》,《Virology of Journal》等多个杂志审稿人。
代表论著:
(1) Chenxi Li, Linjie Zhang, Chenyang Tang, Xuan Chen, Jing Shi, Qingyu Li, Xue Jiao, Jinyao Guo, Bin Wang, Kefan Bu, Abdul Wahaab, Yuguo Yuan, Ming-An Sun, Yanhua Li. DDX3 Regulates the Cap-Independent Translation of the Japanese Encephalitis Virus via Its Interactions with PABP1 and the Untranslated Regions of the Viral Genome. Advanced Science (weinh). 2025 May 8:e2502493.
(2) Chenxi Li, Chenyang Tang,Xiqian Liu, Ying Liu, Linjie Zhang,Jing Shi,Qingyu Li,Mingan Sun, Yanhua Li.E3 ubiquitin ligase MARCH5 positively regulates Japanese encephalitis virus infection by catalyzing the K27-linked polyubiquitination of viral E protein and inhibiting MAVS-mediated type I interferon production. mBio,2025,10.1128/mbio.00208-25.
(3) Chenxi Li,Di Di,Hui Huang,Xin Wang,Qiqi Xia,Xiaochun Ma,Ke Liu,Donghua Shao,Yafeng Qiu,Zongjie Li,Beibei Li,Jianchao Wei.NS5-V372A and NS5-H386Y variations are responsible for differences in interferon α/β induction and co-contribute to the replication advantage of Japanese encephalitis virus genotype I over genotype III in ducklings.[SCI].PLoS Pathogens,2020,16(9)(e1008773).
(4) Chenxi Li, Linjie Zhang, Xuan Chen, Daoyuan Jiang, Jingbo Hu, Jinyao Guo, Jingjing Ding, Xue Jiao, Wenbin Bao, Yanhua Li. Evaluation of the genotype I Japanese encephalitis virus as a stable viral vector for foreign gene expression. ANTIVIRAL RESEARCH, 2023,175:106002.
(5) Chenxi Li ,Xuan Chen, Yanyangzhou,Jingbo Hu,Xinjie Wang, Yanhua Li.Novel reverse genetics of genotype I and III Japanese encephalitis viruses assembled through transformation associated recombination in yeast: The reporter viruses expressing a green fluorescent protein for the antiviral screening assay.ANTIVIRAL RESEARCH,2022,197.
(6) Chenxi Li, Linjie Zhang, Chenyang Tang, Yanbing Zhang, Wen Zhao. Isolation and identification of a duck-derived Japanese encephalitis virus and evaluation of its virulence in mice.Veterinary Microbiology. 2024 Mar;290:109976.
指导学生:
(1)陈萱,2020级硕士研究生,发表SCI论文2篇、授权发明专利2项,毕业就业于默沙东(美国)动物保健中国研发及工艺技术中心;
(2)张林杰,2022级硕士研究生,发表SCI论文3篇、授权国内发明专利1项,美国发明专利1项目,荣获硕士“国家奖学金”、“冯氏企业奖学金”,毕业就业于华淞(上海)生物医药科技股份有限公司;
(3)唐晨阳,2023级硕士研究生,发表SCI论文1篇,2025年转博-硕博连读;
(4)郭文壮,2024级硕士研究生,发表SCI论文1篇,硕士在读;
(5)李静静,2024级硕士研究生,硕士在读;
(6)刘莹,2021级本科生,发表SCI论文3篇,荣获“全国生命科学大赛”国赛一等奖(最高奖),本科在读;

